Nov
26
Nanfang Daily news (Reporter/Ou Xujiang) “South China clinical gene examination center” the other day in Guangdong Province People's Hospital official license establishment. This center's establishment key will make the gene examination for the lung cancer patient, by determined whether to suit after the diagnosis uses the target directly to treatment medicine for example lucky non-Tini, causes the patient quickest benefit. At the appointed time comes this seeing a doctor the lung cancer patient will accept the individuation treatment through the gene examination method. Chinese Anticancer treatment Association clinical tumor Coordinate commission assistant director committee member, a Guangdong Province People's Hospital Vice-President Professor Wu Long said that if the patient has the epidermis growth factor acceptor gene mutation, then compares with the traditional chemotherapy, takes the lucky non-Tini group the non-progress disease survival obviously to excel in the chemotherapy. The patient tumor's epidermis growth factor acceptor gene mutation condition, is forecasts lucky non-Tini the curative effect the key aspect. In Guangdong Province People's Hospital tumor cardiopulmonary internal medicine department Yang Jin records professor to point out that has the epidermis growth factor acceptor gene mutation lung cancer, may after the diagnosis accepts lucky non-Tini to take orally the treatment directly, does not need to endure the chemotherapy again the pain.
Nov
26
??The large-scale lung cancer cause of disease investigation discovery, the indoor small environment and the lung cancer occurrence has the close relation. The indoor microenvironment's pollution mainly includes the following several aspects: ??1st, coal smoke ??The indoor air pollution which mainly comes from prepares food and warms up when burns coal to produce. Prepares food in the bunker coal in the family, the indoor air pollution obviously is higher than the family which prepares food with the fuel gas. Prepares food when with the bunker, the contact mist and dust's female contracts the lung cancer the risk factor obvious markup. The northern area winter indoor warms up when creates indoor always the suspended particle and the benzene third pi daily average density by the bunker for the sanitation standard 4. 4~26. 7 times, these poisons have the high mutagenicity. ??2nd, lampblack ??The Chinese diet culture is fastidious fries, fries, boils, explodes, but fries in oil fries in oil may create in the air the benzene third pi content markup. Specially in these have not pulled out in the lampblack equipment's kitchen, fries frequently, fries, boils, explodes, and human who feels the lampblack stimulation in the ocular region, contracts the lung cancer the risk to increase obviously. The experiment proved that temperature in 270~280? the lampblack has sends the sudden change function. Because the female goes to the kitchen many, the cooking lampblack will increase its trouble lung cancer the danger. Therefore, reduces fries, fries, boils, explodes the number of times and increases pulls out the lampblack equipment, to reduces feminine lung cancer especially important.
??If smokes in the family or public situation some people, passive smoker easily lung cancer. Some research indicated that marries marries to the smoking husband's feminine ratio for does not smoke husband's female to contract the lung cancer the risk markup. ??4th, noxious gas ??In recent years, many families have carried on the room repair. The massive noxious gases send out unceasingly in the repair process in the room, also increased the resident to contract the lung cancer the risk. ??In brief, the lung cancer occurrence is more than a factor synergism result, it has the development probably to need 20 year about the time, but once has the clinical symptoms usual to arrive at the later period, not only has lost the treatment best opportunity, 5 year survival percentage is also low. Therefore the lung cancer first-level prevention is important, namely eliminates the lung cancer the aetiological agent, like the no-smoking, the improvement living conditions, the attention meals balanced, maintain the mental health and so on.
??If smokes in the family or public situation some people, passive smoker easily lung cancer. Some research indicated that marries marries to the smoking husband's feminine ratio for does not smoke husband's female to contract the lung cancer the risk markup. ??4th, noxious gas ??In recent years, many families have carried on the room repair. The massive noxious gases send out unceasingly in the repair process in the room, also increased the resident to contract the lung cancer the risk. ??In brief, the lung cancer occurrence is more than a factor synergism result, it has the development probably to need 20 year about the time, but once has the clinical symptoms usual to arrive at the later period, not only has lost the treatment best opportunity, 5 year survival percentage is also low. Therefore the lung cancer first-level prevention is important, namely eliminates the lung cancer the aetiological agent, like the no-smoking, the improvement living conditions, the attention meals balanced, maintain the mental health and so on.
Nov
25
Every November is a global concern, lung cancer killer as the world's leading today, every year because of lung cancer death toll about 135 million people, more than breast, prostate and colorectal cancer deaths, including the total non-small cell lung cancer accounts for about 80%, and the incidence of lung cancer in recent years in the global scope is rising trend. Of course, lung cancer death, is China's first year sixty million people died of lung cancer. At the same time, our country of non-small cell lung cancer patients with adanced cancer experts, the majority, famous Shanghai thoracic hospital clinical center chief expert professor liao said: Marilyn beauty of lung cancer in the diagnosis, 65% of the late is non-small cell lung cancer diagnosed once you lose the chance of surgical treatment of patients with severe influence, survival and quality of life. At present, chemotherapy remains stage I non-small cell lung cancer (can understand first-line therapy for the treatment of choice), but its effect choice standard has reached platform is undisputable fact and chemotherapy drugs in kill cancer cells, but also human side of normal cells, the patient is often cannot tolerate. In recent years, with the molecular target therapy, the doctor elusive goal is through targeted therapies or with chemotherapy combined breakthrough stage I non-small cell lung cancer chemotherapy, but the bottleneck in the realization of the target is constantly. Professor Lin chang like beauty, because the new targeted drugs and optimizing the treatment of patients with advanced cancer, survival time had significantly extends and even some patients received cure effect, advanced cancer is gradually into a chronic stage. At present in China for non-small cell lung cancer treatment of molecular targeted drugs basically has two kinds, they are the tumor cells of epidermal growth factor receptor (EGFR) signaling channel, and the epidermal growth factor receptor (EGFR) signaling pathways and tumor proliferation and angiogenesis, and have a close relationship. Simply speaking, the role of drugs is within the tumor cells in the small molecules tyrosine kinase (TKI), including a and erlotinib, another kind of role is to extracellular monoclonal antibodies, mainly cetuximab (erbitux). Affiliated hospital of sun yat-sen university internal tension tumor professor: "although the two drugs are applied to tumor cells, but the same signal transmission channels of two classes of drugs and treatment effect mechanism, mainly applicable people are different." Along with the progress of the studies found that if the patients with lung cancer gene mutations EGFR TKI drugs, have very good effect of treatment, and patients with no mutations, not only can obtain treatment effect, still can cause cancer. Current European stage I non-small cell lung cancer patients to use TKI drugs as a first-line therapy, the patient must first have genetic mutations, EGFR in domestic and, on the other hand, due to the complexity of the test result of the patient, in addition to the tumor tissue is not easy access, the degree of EGFR genetic testing is not high, only in some big cancer center has developed. This tension is ready to use for professor calls TKI drugs for the treatment of patients with lung cancer, best early detection of EGFR
Nov
25
??Every year's November is “the international lung cancer attention month”. According to world lung cancer alliance newest issue's in 2009 the lung cancer correlation data, the lung cancer casualty is bigger than the colon cancer, breast cancer, the cancer of the pancreas and the prostate gland cancer's sum of casualty. China is the world tobacco consuming country, is also in the world lung cancer patient most countries. The lung cancer already became our country malignant tumor cause of death the first place, in every 3-4 cancer's death patient, has one to die of the lung cancer. ??To propagandize “is far away from the tobacco attention lung cancer” the idea and the scientific standard lung cancer method of treatment to the public, the medical department prophylaxis control bureau and the Chinese Anticancer treatment Association recently together started in 2009 "Hand in hand Hope" the lung cancer topic propaganda month activity. ??The public is right “the second-hand smoke” the harm understanding insufficiency ??The public already knew very well “a smoke” harm, but is right “the second-hand smoke” understanding also by far insufficient. The investigation showed that lives together for a long time with the smoker the human, will contract the lung cancer the probability to enhance 25%, but will be compelled in the work medium and long-term to attract the second-hand smoke smog also to increase the trouble lung cancer the danger. The newest research also discovered that by the smoking result's lung cancer, the treatment result is lower than the non-smoker to contract the lung cancer obviously, the surgical operation risk also obviously is higher than the non-smoker lung cancer patient. The smoking result's lung cancer is insensitive to the chemotherapy medicine, chemotherapy effectiveness has 30%-40%, moreover also does not have the corresponding target at present to the treatment medicine. ??Chinese Anticancer treatment Association Popular science Propaganda department minister, capital Medical college lung cancer diagnosing and treating center director repairs benefits professor to point out: “at present, China increases the lung cancer case every year in 500,000 to 600,000, if does not control the tobacco spread and the reduced smoking population, does not pay attention to the environmental protection and the air pollution, then theoretically speaking, China achieves the lung cancer morbidity peak to 2025, every year will increase the lung cancer patient to reach 1,000,000 people!” ??The lung cancer method of treatment had made great strides ??Capital Medical college attached Beijing was exposed to the sun hospital thoracic surgery Director Professor Li Hui to introduce that the early lung cancer was treats by the surgical operation primarily. The traditional lung cancer surgery wound is very big, has affected the technique, after enormously after recovery and patient technique, quality of life. Along with the surgical department technology and the anaesthesia technology's swift development, many lung cancer's surgical treatments may through micro create the surgery now to complete safely, micro creates the surgery to treat has become the lung cancer surgical treatment the development direction. ??However, because the non-cellule lung cancer occupies the lung cancer case total 80%, as soon as and the patient passes through diagnoses 80% is the mid and late stage or the later period, lost has carried on the opportunity which the radical cure surgical operation treated. ??The target has brought the new hope to medicine coming out with the clinical practice for the later period non-cellule lung cancer's treatment. The target only affects to the medicine in the lung cancer cell, has not affected to the normal cell, moreover avoided the white blood cell which the traditional chemotherapy medicine caused dropping, the disgusting vomit and so on intense side effect, obviously improved patient's quality of life. ??Tips: ??The cough must pay attention continually ??The early lung cancer clinical symptoms are often atypical, when therefore appears continues in the cough which, the expectorate, the phlegm the belt blood, the chest stuffy, feels suffocated, becomes emaciated and so on symptoms, should early arrive at the hospital to make the corresponding inspection, removes the lung cancer. In recent years, along with the phantom study technology's and so on X, CT and MRI development, the lung cancer diagnosis rate had the very big enhancement, but it is noteworthy that partial patients, even many basic unit medical service unit's doctor also has “the dependence phantom study inspection may diagnose the lung cancer” the erroneous zone in the understanding. In fact, the phlegm cytology inspection, the blood serum tumor tracer inspection, the textile fiber bronchoscope inspection has the unwise to underestimate function in the lung cancer diagnosis.
Nov
25
“in the later period non-cellule lung cancer's treatment domain, affects in the tumour cell surface epidermis growth factor acceptor's anti-EGFR target to the treatment medicine, also used with the chemotherapy, has harvested the good clinical effect.”The other day, at the Shanghai international lung cancer forum, China Medical Association Tumor Academic society permanent committee member, Shanghai lungs tumor clinical medicine center director, Shanghai Chest Hospital Hospital chief expert Professor Liao Mei Lin has transmitted this news. She indicated that at present the chemotherapy unites certain target's to surpass the pure chemotherapy after treatment effect. This caused a present later period lung cancer treatment the strategy already gradually to transform from the pure chemotherapy into the target to the medicine union chemotherapy. The lung cancer is the current domestic and foreign disease incidence rates and the mortality rate highest malignant tumor, 80% above right and wrong cellule lung cancer. Because the non-cellule lung cancer lacks the model easily the symptom which and the symptom distinguishes, was discovered when majority had already lost the surgery opportunity mid and late stage. Formerly, doctor regarding later period non-cellule lung cancer patient's treatment too many choices, the most main treatment method had not been a chemotherapy. With does not carry on the active treatment to compare, the chemotherapy can lengthen the later period patient's life (this time length to use “position total lifetime” to indicate that namely has 50% patient's survival to be able to achieve this time). Including non-cellule lung cancer many malignant tumor occurrence development with tumour cell surface one kind of named “epidermis growth factor acceptor” (i.e. EGFR) the member concerns. This kind of member can promote the tumor growth and the proliferation. But affects specially in the EGFR medicine can suppress the tumor the growth and the shift. Now we already might obtain this kind of kind of medicine in the later period non-cellule lung cancer treatment - - “the anti-EGFR target to the treatment medicine”. West proper past Shan Kang takes one kind of anti-EGFR target to the treatment medicine, can affect from the tumour cell in EGFR, then the impediment tumor's growth and the proliferation, obviously lengthen the lifetime. Introduced from German Hamburg's chest tumor expert Dr. Kenneth at the lung cancer forum a 13th world lung cancer conference's item gathers together the analysis result: Internationally the development many clinical research result showed that with uses the traditional chemotherapy to compare purely, west the proper past list anti-union chemotherapy takes the later period non-cellule lung cancer patient's primary treatment, can obviously lengthen patient's position total lifetime. The treatment starts within 3 weeks to present the acne type skin rash's patient, the extension life function is more remarkable, the position total lifetime has achieved for 15 months. But accepts the traditional chemotherapy patient's position always survives contract for 10 months. Therefore, the anti-EGFR target proper past Shan Kang is treats the later period lung cancer to the medicine west the powerful weapon.






